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Hyperglycemia Diabetes is associated with the accelerated disappearance of capillary endothelium [159], morphological and functional alterations of ECs [160], and the weakening of intercellular junctions [161], which ultimately leads to ECD

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Current single-nucleus RNA-seq datasets from human AD tissue reveal distinct ferroptosis-related transcriptional programs in glial cells, including upregulation of TFRC, FTH1, SLC40A1, and ACSL4, which indicate enhanced iron turnover and lipid peroxidation susceptibility (Leng et al., 2021)

Phytochemicals targeting Alzheimers disease via the AMP-activated protein kinase pathway, effects, and mechanisms of action

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